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An Unusual Cause of Pancreatic Metastasis: Pleomorphic Sarcomatoid Carcinoma of the Lung

Context Sarcomatoid carcinomas are rare malignant neoplasms that have both carcinomatous and sarcomatous components and involve mostly lungs, kidneys and pancreas. Case report In this case report we present a rare case of 60-year-old male patient with pleomorphic sarcomatoid carcinoma of the lung presenting with obstructive jaundice. The biliary obstruction was caused by head of pancreas lesion metastasized from the lung. The diagnosis was made by the endoscopic ultrasound-guided fine-needle aspiration of the pancreatic head metatstatic lesion. Thyroid transcription factor-1 immunostain confirmed the lung origin of the pancreatic head lesion. Among lung cancers, small cell carcinoma and adenocarcinoma have been associated with pancreatic metastasis. Conclusion To the best of our knowledge we hereby present the fourth reported case of pleomorphic sarcomatoid carcinoma of the lung with metastasis to the pancreas.

Author(s): Tariq Hammad, Yaseen Alastal, Muhammad Ali Khan, Weihong Li, Luis DeLasCasas, Osama H Alaradi, Ali Nawras

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