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Bladder Metastasis from Pancreatic Ductal Adenocarcinoma: Case Report and Comprehensive Literature Review

Context Pancreatic ductal adenocarcinoma is the seventh most frequent cause of cancer worldwide. Around 50% of the patients with pancreatic ductal adenocarcinoma have metastases synchronous to the diagnosis. The most common metastatic location of this tumor is the liver, the peritoneum and the lungs. Pancreatic ductal adenocarcinoma - related bladder metastases are very infrequent and may mimic primary urothelial malignancies. Case report We report the case of a pancreatic bladder metastasis fortuitously discovered two years after the diagnosis of a pancreatic adenocarcinoma. We reviewed also all the cases described in the literature. Conclusion Bladder metastases are very rare and could be wrongly consider as urothelial carcinoma. It must be suspected in patients with pancreatic ductal carcinoma and unique bladder tumor.


Caroline Lacombe, Louis de Mestier, Yohann Grassano, Margot Bucau, Magaly Zappa, Philippe Lévy

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