All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


Factors Associated With the Development of Diabetes Mellitus Following a First Episode of Acute Pancreatitis

Aim To determine the prevalence and risk factors of new-onset diabetes mellitus in patients after a first episode of acute pancreatitis. Methods A retrospective study design was used. Patients diagnosed with a first episode of acute pancreatitis in the emergency department of a tertiary medical center in 2010-2016 were followed for the occurrence of diabetes mellitus. Clinical data were collected from the medical records and compared between patients with and without a subsequent diagnosis of diabetes. Results Of 500 patients who presented with a first episode of acute pancreatitis during the study period, 41 (8.2%) were subsequently diagnosed with diabetes and 29 (5.6%), with pre-diabetes, and 312 (62.4%) had normal glucose levels; the remainder had pre-existing diabetes. Mean duration of follow-up was 6.7±3.1 years, and mean interval between diagnoses was 1.46±1.4 years. Compared to the patients with normal glucose levels, the diabetes group was characterized by older age (64±17 years vs. 54±21 years, p<0.01) and higher blood pressure values (systolic: 147±21 mmHg vs.131±23 mmHg, p<0.01; diastolic: 83±15 mmHg vs.74±13 mmHg, p=0.013) at presentation to the emergency department, higher score on the Bedside Index for Severity in Acute Pancreatitis (BISAP; 1.22±0.85 vs. 0.88±0.87, p=0.02), and higher rate of non-biliary pancreatitis (45% vs. 26.8%, p=0.02). Conclusions Risk factors for the development of diabetes after a first episode of acute pancreatitis include high blood pressure, high BISAP score, and non-biliary etiology. These findings in patients who present to the emergency department with acute pancreatitis should alert the clinician to the need for close monitoring for diabetes.

Author(s): Genady Drozdinsky, Alon Grossman, Shachaf Shiber

Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+

Abstracted/Indexed in

  • Index Copernicus
  • Academic Journals Database
  • Genamics JournalSeek
  • Academic Keys
  • China National Knowledge Infrastructure (CNKI)
  • CiteFactor
  • Scimago
  • British Library
  • Electronic Journals Library
  • Directory of Research Journal Indexing (DRJI)
  • WorldCat
  • Emerging Sources Citation Index (ESCI)
  • EBSCO Host
  • MIAR
  • International Committee of Medical Journal Editors (ICMJE)
  • University of Zurich - UZH
  • University Grants Commission
  • SWB Online-Katalog
  • Scholarsteer
  • Geneva Foundation for Medical Education and Research
  • Secret Search Engine Labs
Flyer image