Aim In the treatment of acute biliary pancreatitis (ABP), a cholecystectomy is used to prevent acute pancreatitis recurrences. In this study, we aimed to compare the results of early and late-stage LC in patients hospitalized in our clinic with an ABP diagnosis. Material and Methods The patient group was comprised of 35 females (77.8%) and 10 males (22.2%). The 22 patients who underwent LC after ABP treatment were in Group 1, while the patients who were given a two-month interval after the ABP treatment and then underwent LC were in Group 2. Results The average age of the patients was 56 (range: 26–93) years. The average hospital stay was 13.18 days in Group 1 and 8.3 days in Group 2. The mean duration of LC was 57.8 minutes in Group 1 and 45.7 minutes in Group 2 (p < 0.01). The conversion to a conventional cholecystectomy was performed in three (13.6%) patients in Group 1 and two (8.7%) in Group 2. Postoperative complications were seen in four (18.1%) patients in Group 1 and four (17.4%) patients in Group 2. Acute pancreatitis was seen again in one (4.5%) patient in Group 1 and two (8.7%) patients in Group 2. Conclusion In this study, we showed that cholecystectomy surgery can be performed safely after the ABP picture regresses.