A Rare Ocurrence of Small Cell Carcinoma in Pancreas: A Case Report

Introduction Small cell carcinoma is an aggressive tumor with poor prognosis. Lung is the predominant site in 18-20% of the patients1. Overall, 2.5% of all small cell carcinoma arises in the extra-pulmonary site. Pancreatic small cell carcinoma has aggressive nature thus patients present late with advanced disease or with metastases. Survival of patient is between 2 to 9 months. There is neither any staging system nor any accepted guideline regarding the management of small cell carcinoma of pancreas. We present a rare case of pancreatic small cell carcinoma. This will enlighten us about clinic-pathological factors and prognosis of disease. Case discussion A 53 year old female with no past history of medical illness or addiction, married with 6 kids, presented with history of jaundice along with weight loss for 1 month. Computed Tomography Scan showed growth in peri-ampullary region. Endoscopic retrograde cholangio-pancreaticography and stenting was performed. Specimen was taken from peri-ampullary growth which showed small cell carcinoma of pancreas. Conclusion Small cell carcinoma is an uncommon neoplasm with only a few cases reported in literature. Rarity of disease makes it difficult to draw conclusion from this case report. However, it will be an addition in the literature for better understanding of the disease. Prospectively, meta-analyses and systemic reviews are required to understand it.


Kashmala Amjad, Osama Shakeel, Muhammad Asif Noor, Faizan Ullah, Abdul Wahid Anwer,
Irfan Ul Islam Nasir, Alishba Naeem, Faisal Hanif

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