Can Prophylactic Drains After Pancreaticoduodenectomy Be A Risk Factor for Organ/Space Surgical Site Infection?

Introduction Although some authors have reported that retrograde infection by longterm placement of prophylactic drain may be the main cause of organ/space surgical site infection after pancreaticoduodenectomy. Materials and Methods The study included 93 patients who underwent pancreaticoduodenectomy. We assessed the risk factors for organ/space surgical site infection and examined the microorganisms detected at organ/space surgical site infection to determine the origin of microorganisms. Results Of the 93 patients, 29 were included in the organ/space surgical site infection+ group. The risk factors for organ/space surgical site infection on univariate analysis were blood transfusion (OR, 2.70; p <0.05), the amount of peritoneal lavage <5,000 mL (OR, 3.08; p<0.05), open type of prophylactic drain (OR, 2.92; p<0.05), and the incidence of pancreatic fistula (OR, 7.54, p<0.001). The microorganisms, detected in cultured specimen from prophylactic drain at organ/space surgical site infection, belonged to intestinal flora in 22 out of 29 patients (75.9%), and 30 of all 48 detected microorganisms (62.5%) were occupied by those of intestinal flora. Conclusion We confirmed that pancreatic fistula was the most significant risk factor. Based on the microorganisms identified, retrograde infection via drain placement could not be confirmed; therefore, the time of the drain removal should be carefully considered.


Takashi Orii, Yukihiko Karasawa, Hiroe Kitahara, Masaki Yoshimura

Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+
30+ Million Readerbase
Recommended Conferences
Flyer image
Abstracted/Indexed in
  • Index Copernicus
  • Academic Journals Database
  • Genamics JournalSeek
  • Academic Keys
  • China National Knowledge Infrastructure (CNKI)
  • CiteFactor
  • Scimago
  • British Library
  • Electronic Journals Library
  • Directory of Research Journal Indexing (DRJI)
  • WorldCat
  • Emerging Sources Citation Index (ESCI)
  • EBSCO Host
  • MIAR
  • International Committee of Medical Journal Editors (ICMJE)
  • University of Zurich - UZH
  • University Grants Commission
  • SWB Online-Katalog
  • Scholarsteer
  • Geneva Foundation for Medical Education and Research
  • Secret Search Engine Labs