Can Roxithromycin and Betamethasone Induce Acute Pancreatitis? A Case Report

Context Acute pancreatitis has been reported in a few cases treated with macrolides or glucocorticoids. Case report We report the case of a 58 year old patient who, after 2 days of treatment with roxithromycin and betamethasone, manifested acute pancreatitis. Other causes of the disease were ruled out. No re-occurrence of pancreatitis was observed in a 16 month follow-up. Conclusion Our case sheds new light on glucocorticoid pancreatotoxicity and confirms the role of macrolides as potential pancreatotoxic drugs.


Pascal Renkes, Nadine Petitpain, Fran?oise Cosserat, S?bastien Bangratz, Philippe Trechot

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