Serous Cystadenocarcinoma of the Pancreas Presenting with Liver Metastases: Case Report and Literature Review

Serous cystic neoplasms of the pancreas are usually benign. Malignant serous cystic neoplasm is a rare clinical entity. We report a case of a 45-year-old man presenting with metastatic liver lesions on ultrasound. Computed tomography scan showed a hypervascular solid lesion arising in the pancreatic body and invading the celiac axis and portal vein with liver metastases. Ultrasound-guided liver biopsy diagnosed a serous cystic neoplasm, indistinguishable from serous cystadenoma. Based on clinical, radiological and pathological correlation, the diagnosis of cystadenocarcinoma was established. There are few reported cases of malignant serous cystic neoplasms in which malignancy was confirmed. Although rare in males, cystadenocarcinoma should be considered in the differential diagnosis of patients presenting with a pancreatic mass and liver metastasis.


Marcos Vinicius Perini, Fabiana Roberto Lima, Nathan Elie Frenk, Hilton Muniz Leão Filho,Fabricio Ferreira Coelho, Jaime Arthur Kruger, Manoel de Souza Rocha, Paulo Herman

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