Abstract

Xanthogranulomatous pancreatitis is an extremely rare histological subset of pancreatitis characterized by chronic destructive granulomatous inflammation. Here, we report a 23-year-old man who was found to have xanthogranulomatous pancreatitis complicated by pancreas pseudocysts that infiltrated into spleen, stomach, transverse colon and omentum. The lesion persisted through medical treatments such as dietary modification, pharmacotherapy, and endoscopic intervention. Though this is benign entity, only radical resection as a last resort cut off a chain reaction of inflammation of xanthogranulomatous pancreatitis.