Abstract

Context Diffuse large B-cell lymphoma is the commonest form of non-Hodgkin lymphoma. Gastro-intestinal tract and bonemarrow are common extra-nodal sites of lymphomatous involvement. Case report A 54-year-old woman presented withacute onset epigastric pain. On evaluation, raised serum amylase and radiological features of acute pancreatitis weredetected. Gastroscopy revealed thickened folds in distal stomach, which on histopathology revealed large B-cell lymphoma.Subsequently, the patient developed extra-hepatic biliary obstruction due to peripancreatic lymph nodal mass that wasrelieved with plastic biliary stenting. Subsequent chemotherapy regime directed against lymphoma led to resolution oflymphoma. Conclusion In this patient , pancreatitis was the initial presentation of primary gastric lymphoma, which has notbeen commonly reported and therefore should be considered in the etiological workup.